The main difference between therapeutic and research approaches that preceeded Psychosocial Genomics is that the models developed to date, although effective, they were often at an only level, negleting the others, thus losing sight of connectivity issue between the different parts and the complexity of the whole. Both in Psychology and Psychotherapy, on the one hand, we have had approaches that have focused attention exclusively on the psychological dimension, leaving out the body size, while on the other hand, we had models that have considered the only body size in both the phenomenological and psycho-physiological dimension. In fact so far, we have not had a theoretical model that would contain within it all processes and operating levels of mankind in his totality. I believe that this is essentially due to the difficulty of holding together this complexity and at the same time finding the connections between different levels of analysis. The Psychosocial Genomics tries to point out and simultaneously define the highest level of functioning and even seemingly as far away from the cultural subject, moving on to the social, interpersonal, until reaching the intrapersonal one. These levels are closely connected with each other and act directly on the person at phenomenological, behavioral and psychological levels, but also to an even deeper level that reaches the our genes expression, making new proteins and brain plasticity.

We could represent these different levels as concentric circles containing one another where they influence each other. Intrapersonal level contains within it: mind, brain, body and genes. They are intimately connected each other and communicate constantly through an information transduction that makes sure the data initially created within a specific level of operation, such as mental, are transformed into signals from the brain, gene expression and sinthesys of new proteins. The process continues when the signals from the proteins become synaptogenesis and neurogenesis with inevitable effects on the brain and mind. Unlike previous psychological and psychoterapeutic models, Psychosocial Genomics is the first epistemological, research and intervention model that has as its objective the analisys and explanation of what you think is happening apparently to a single level of our operation but in reality it is affecting every aspect of our totality trough the transduction information. The journal and its community of reference is holding together all this different levels within a circularity that makes the two-way flow of communication and changes, and thanks to this exstraordinary possibilty of construction and deconstruction plastically. In this perspective we hope to have more and more support, scientific and cultural contribution from all scholars and clinicians who care about this prospect. Ad Maiora

Mauro Cozzolino